Mounjaro (tirzepatide) Injection

Mounjaro® is an MHRA-approved prescription injection that was initially developed for the treatment of Type 2 diabetes. During use, many patients experienced notable weight reduction, leading to its use as a medical option for weight management. The active ingredient in Mounjaro is tirzepatide.

Tirzepatide works by imitating specific hormones naturally released in the body that help regulate appetite and digestion. This can reduce hunger, increase feelings of fullness, and slow how quickly food is processed.

For best results, Mounjaro® should be used as part of a wider plan that includes a calorie-controlled diet and regular physical activity.

Mounjaro® may be prescribed to adults who meet recognised medical criteria for weight management. You may be eligible if you:

• Have a BMI over 30, or

• Have a BMI over 27 alongside a weight-related health condition, such as high blood pressure or heart disease

If you are currently taking prescription medication or managing an existing medical condition, this should be discussed with a healthcare professional before starting treatment.

Examples of weight-related health conditions include high blood pressure, abnormal blood lipid levels, obstructive sleep apnoea, cardiovascular disease, prediabetes or type 2 diabetes.

Mounjaro is prescribed alongside a reduced-calorie diet and increased physical activity. Meeting the BMI criteria does not automatically mean that treatment is suitable. A prescriber will review your health information, medical history and current medicines before deciding whether Mounjaro is appropriate for you.

Weight regulation is influenced by several factors, including hormones that control hunger, blood sugar levels, and energy use. Two key hormones involved in this process are GLP-1 and GIP, which are released by the gut after eating.

Mounjaro® activates these same hormonal pathways, helping to slow stomach emptying and reduce appetite. This supports improved satiety and more stable blood sugar control, which can assist with long-term weight management when combined with healthy lifestyle changes.

Mounjaro® is administered once weekly using a pre-filled injection pen. Your healthcare provider will explain the injection process during your consultation.

You can take your dose at any time of day, with or without food. You should follow the instructions provided with your specific Mounjaro KwikPen and the advice given by your healthcare professional.

Mounjaro® can be injected into:

• The abdomen

• The thigh

• The back of the upper arm (with assistance if needed)

Injection sites should be rotated with each dose. If you also use insulin, Mounjaro should be injected at a different injection site.

Always read the instructions supplied with your Mounjaro KwikPen before using it. If you are unsure how to use your pen or inject your dose, speak to your prescriber or pharmacist.

Mounjaro® is available in multiple strengths and follows a gradual dose-increase schedule to help minimise side effects.

• Treatment usually starts at 2.5mg once weekly

• This starting dose is typically used for 4 weeks to allow adjustment

• Dose increases may be recommended by your doctor based on tolerance and response

Do not take more than one dose per week or adjust your dose without medical advice.